Post Doctoral.Post Doctoral.AssociateUniversity of Pittsburgh

The University of Pittsburgh, Ophthalmology Department is searching for a Post Doctoral Associate. This project will clarify the isoform-specific roles of BSG in retinal physiology and establish their importance in metabolic homeostasis. Ultimately, it may uncover novel therapeutic strategies for diseases such as retinitis pigmentosa, retinopathic diabetic, or age-related macular degeneration. Along with the research added repressibilities would be to help train Students and new lab members, Participate in publications from the lab, verify lab supplies are kept in stock and participate in procedure creation.

Essential Skills (must have at entry)

1. Molecular and Cellular Biology

• Solid experience in gene and protein analysis (qPCR, Western blot, cloning)

• Understanding of alternative splicing mechanisms

• Familiarity with RNA-binding proteins (e.g., HNRNPs is a plus)

2. Experimental Design & Data Analysis

• Ability to design rigorous experiments and interpret complex datasets

• Experience with statistical analysis and reproducibility standards

• Scientific writing skills (papers, grant contributions)

3. Basic Metabolism Knowledge

• Understanding of cellular metabolism (glycolysis, mitochondrial function, redox balance)

• Familiarity with metabolic stress pathways

Strongly Preferred Skills

1. Retinal Biology / Neuroscience

• Knowledge of photoreceptor biology and retinal organization

• Experience with retinal models (mouse or in vitro systems)

2. Mouse Genetics and In Vivo Work

• Experience with transgenic or knockout mouse models

• Phenotyping (histology, immunohistochemistry, functional assays such as ERG is a plus)

3. Protein Interactions and Signaling

• Experience studying signaling pathways (e.g., ligand–receptor interactions like RdCVF–BSG)

• Techniques such as co-immunoprecipitation or proximity assays

PhD in Molecular or Cellular Biology or like degree required

The University of Pittsburgh is an equal opportunity employer / disability / veteran.